The 11th televised debate of the Republican party's presidential hopefuls, broadcast on Fox News, made for many a cringeworthy moment, one of which involved Trump's hands and manhood.
The attacks were also loud between Trump and Ted Cruz.
It's a far smaller field than the 17 Republican candidates that began the race for the 2016 presidential nomination, but one that is still splintered between the incendiary NY businessman and three experienced politicians.
Within five minutes of the debate's opening, Trump had seemingly bragged about the size of his genitals. "And frankly, had I heard him say the things I've heard him say now, I wouldn't have welcomed his endorsement". "I guarantee", he assured the audience.
Rubio defended his attacks, saying it was Trump who started the insults. "If there's anyone who's ever deserved to be attacked that way, it's Donald Trump".
Mr. Rubio and Mr. Cruz have for months failed to unequivocally condemn Mr. Trump for his hate speeches.
Trump and Cruz also tangled in a heated exchange on nominating conservative Supreme Court justices, with Cruz repeatedly asking Trump to "breathe, breathe, breathe".
Missouri has first known case of Zika virus
According to the CDC , babies with microcephaly often have smaller head sizes and brains that might not have developed properly. The Zika virus is usually spread and carried by mosquitos and is strongly related to the West Nile and yellow fever.
The low-polling Kasich stayed out of the political dog fight. It's the KKK! But here's what I hate most: "He could be our next President", Ms Clinton said.
The two will take to the debate stage in Flint, Michigan, on Sunday.
The party's 2012 nominee, Mitt Romney, added his support to that effort Thursday.
John McCain, the 2008 Republican candidate, supported Mr. Romney's views. He says, "he wants to be back in the game". When there were some foul balls, be able to call them and see if I can't keep people guided on the path to becoming our next president.
He insisted he would win the case but Mr Rubio claimed he was trying to "con people into giving him their vote, just like he conned people into giving him their money".
"We're going to have a party that's going to have to somehow justify to itself why it's voting for this man", Rubio said.
Democratic presidential frontrunner Hillary Clinton has slammed her Republican rival Donald Trump for his hate-filled vision and has described the real-estate tycoon as "terrifying".