More evidence that aspirin lowers risk of cancer

The US Preventive Services Task Force recommends aspirin to prevent colorectal cancer and cardiovascular disease among many adults. Generally speaking, the report said the aspirin regiment was associated with a 3 percent lower risk for all cancers.

Researchers looked at data from 1986 of 88,084 women (aged 30-55) and 47,881 men (aged 40-75) participating in two large studies.

Experts today said that people who are at particular risk of bowel cancer should consider regularly taking a low dose of aspirin, especially if they might also benefit from the fact that aspirin also reduces heart disease.

A large-scale study spanning more than 30 years found that people who took aspirin for several years were less likely to develop colon cancer. The event will offer free in-home colorectal cancer screening kits, lung cancer risk assessments, education on cancer risk factors and affordable blood testing.

Aspirin use, they say, could complement colorectal cancer screening and could be beneficial regardless of endoscopy status.

Two studies have consistently shown that the regular usage of aspirin causes a drop in the risk of contracting cancer.

The latest findings on aspirin and cancer come from an analysis of 2 long-term population studies in the US. Regular use of aspirin twice or more per week was associated with a 3 percent lower risk for all cancer.

Bottom line: Taking aspirin regularly might prevent 17 percent of colon cancers among those who are not screened with colonoscopy and 8.5 percent of colon cancers among those who are, according to research.

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Taking just two aspirin a week can protect against cancer, potentially preventing 10,000 cases a year.

According to Dr Andrew Chan from the Massachusetts General Hospital, individuals with a previously established family history of gastrointestinal cancers must seek medical advice and evaluate the prospect of using aspirin as a major prevention measure again such cancers.

Aspirin's protective benefit appeared after five years of continuous use at dosages ranging from a half to 1.5 standard tablets a week, or one low-dose pill a day. Thus it is clear that by supplementing with aspirin, the strength of cancer prevention methods such as colonoscopy and other screening techniques could be boosted. About 9 per cent of colon cancers could be prevented with regular Aspirin use among people who do get screened. However, research also points out that consistent aspirin use is not associated with a reduced risk of other cancers. However, questions remain on optimal dose and duration of use, and whether there may be effects on other cancers.

The main limitations with observational cohort studies are the possibility that other health and lifestyle characteristics of the individuals may be involved in any link.

"A colorectal cancer diagnosis is never expected, and it's never easy", Tomblin said. Nationwide, deaths due to colon cancer have been on the decline, mostly due to earlier detection.

And for bowel cancer, which affects 41,000 people in Britain every year, the risk of diagnosis was reduced by 19 per cent.

The research was based on observational studies, so it is not as strong as a randomized controlled trial.

Probably most importantly - aspirin isn't without side effects.