Real Madrid with the loss of goal scoring form from Cristiano Ronaldo, who has gone nearly five games without a goal in the competition, will look to French striker Karim Benzema who has scored four of Real Madrid's last six Champions League goals and will be hoping to add to his career total of 53 in the competition.
Napoli will host the second leg on 7 March, in Italy. Man for man, no other team in the competition has such quality and strength in depth, except maybe perhaps Bayern Munich. The ball bounced once before hitting the net near the far post as Navas desperately tried to recover.
"The 4 has given me a lot of luck and has accompanied me throughout my career with Real, but don't think that I haven't considered changing it for 93", he said.
We didn't have to wait long for the first goal of the match, and what a goal it was.
Madrid now have a comfortable lead in the Spanish Liga, but at times have been less than impressive, it will be fascinating to see how they and an in-form Napoli perform in a game which offers no second chances. "Maybe we made too many mistakes, this will only push us to work even more".
Indonesia disaster agency says 7 killed in Bali landslide
Mr Sutopo said extreme rain, with 145 millimetres in one day, had occurred in the regency of Karangasem on Wednesday. The landslides hit Songan village of Bangli district, falling and destroying five houses at about 11 pm Thursday.
The lead lasted 10 minutes as Real drew level when Dani Carvajal's arrowed cross was headed powerfully into the net by Benzema.
Madrid had won 23 of their previous 32 home matches against Italian opposition, yet their only two-legged victory over a team from the peninsula came last season against Roma, also in the round of 16.
Toni Kroos put Real 2-1 up four minutes into the second half after being picked out by Cristiano Ronaldo.
Despite the eventual dominance that Madrid showed, Napoli can take heart in the fact that they are categorically still in the tie, with the Madrid defence clearly fearful of their frontline, and with Insigne having secured a crucial away goal for them.